Phagotherapy

Phage therapy involves the use of bacteriophage viruses, known as phages, to treat certain infectious diseases of bacterial origin. Phage proteins are also at the heart of Vetophage’s technology, and are now the preferred choice.
Resistance occurs when a bacterium adapts and becomes resistant to the antibiotics used to treat the infections it causes.
We often talk about antibiotic resistance in humans, but much less so in animals. The use of antibiotics in farm animals leads to the emergence of antibiotic resistance in potentially lethal bacteria.
Researchers from the Swiss Federal Institute of Technology Zurich (ETH Zurich), the Princeton Environmental Institute (PEI) and the Free University of Brussels, found that between 2000 and 2018, the proportion of antibiotics with resistance rates above 50% in developing countries soared: from 0.15 to 0.41 in chickens, and from 0.13 to 0.34 in pigs.
Multi-resistant” bacteria are becoming increasingly prevalent, which could ultimately compromise the health of livestock farms and the people who consume these animals.

Phagotherapy

Advantages of phages and phage proteins

Phages are found in nature. It is estimated that there are around 1030 phages with 108 different genomes on the planet, providing an almost unlimited reservoir of therapeutic antibacterial agents from which to draw.

Phages target an infection precisely, damaging only the bacterial cells they are designed to kill.

Lytic phages can kill antibiotic-resistant bacteria.

Phage therapy has far fewer side effects than antibiotics.

The process using natural phages is fast and inexpensive, unlike antibiotics whose development is long and very costly.

PHAGE BANK

Our phage library

Vetophage has extensive experience in phage research and characterization. Our phage library is constantly being enriched with new phage isolates.

We currently have phages or phage proteins for the following bacteria:

Staphylococcus aureus

Streptococcus uberis

Vibrio parahaemolyticus

Escherichia coli

Staphylococcus pseudintermedius